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This spring, discover a way to cool off your personal summer

BIJUVA is the first and only FDA-approved combination of bio-identical* estradiol and bio-identical progesterone together in a single oral capsule. BIJUVA is a new treatment for moderate to severe hot flashes due to menopause in women with a uterus.

AVAILABLE
SPRING 2019

* There is no evidence that bio-identical hormones are safer or more effective than synthetic hormones.

Menopause aka
"What the heck is
going on?"

The symptoms you know and the effects you haven't considered.

Find out what to expect

You don't have to
menopause alone

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IMPORTANT RISK INFORMATION

  • Do not use estrogens with or without progestogens to prevent heart disease, heart attack, strokes or dementia (declines of brain function)
  • Taking estrogens with progestogens may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots
  • Taking estrogens with progestogens may increase your chance of getting dementia, based on a study of women 65 years of age or older
  • Taking estrogens alone may increase your chance of getting cancer of the uterus
  • You and your healthcare provider should talk regularly about whether you still need treatment with BIJUVA

Do not take BIJUVA if you:

  • have any unusual vaginal bleeding. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause
  • currently have or have had certain cancers. Estrogens may increase the chances of getting certain types of cancers, including cancer of the breast or uterus. If you had cancer, talk with your healthcare provider about whether you should take BIJUVA
  • currently have or have had blood clots
  • had a stroke or heart attack
  • currently have or have had liver problems
  • have been diagnosed with a bleeding disorder
  • are allergic to BIJUVA or any of its ingredients
  • are pregnant, think you may be pregnant, or plan to become pregnant, or are breastfeeding.

WARNINGS

Tell your healthcare provider about all of the medicines you take and all of your medical conditions, including if you:

  • have high levels of fat in your blood (triglycerides)
  • have any unusual vaginal bleeding
  • have certain medical conditions that may become worse while you are taking BIJUVA such as: asthma (wheezing), epilepsy (seizures), diabetes, migraine, a genetic problem called porphyria, endometriosis, lupus, angioedema (swelling of the face or tongue), hypertension (high blood pressure), problems with your heart, liver, thyroid or kidneys, benign breast disease, have high calcium in your blood, are going to have surgery or will be on bed rest, are pregnant or think you may be pregnant, or are breastfeeding.

Call your healthcare provider right away if you get any of the following warning signs:

  • New breast lumps
  • Unusual vaginal bleeding
  • Changes in vision or speech
  • Sudden new severe headaches
  • Severe pains in your chest or legs with or without shortness of breath, weakness and fatigue
  • Vomiting.

The most common side effects of BIJUVA include:

  • Breast tenderness
  • Headache
  • Vaginal bleeding
  • Vaginal discharge
  • Pelvic pain.

USE

BIJUVA (estradiol and progesterone) capsules, 1mg/100mg, is used after menopause to reduce moderate to severe hot flashes in women with a uterus. BIJUVA is a prescription medicine that contains two hormones, estrogen and progesterone.



The risk information provided here is not complete. To learn more, review the BIJUVA Patient Information and talk about BIJUVA with your healthcare provider or pharmacist.

These are not all the possible side effects of BIJUVA. You may report side effects to the FDA at www.fda.gov/medwatch or by calling 1-800-FDA-1088. You may also report side effects to TherapeuticsMD at 1-888-228-0150.

IMPORTANT RISK INFORMATION

  • Do not use estrogens with or without progestogens to prevent heart disease, heart attack, strokes or dementia (declines of brain function)
  • Taking estrogens with progestogens may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots
  • Taking estrogens with progestogens may increase your chance of getting dementia, based on a study of women 65 years of age or older
  • Taking estrogens alone may increase your chance of getting cancer of the uterus
  • You and your healthcare provider should talk regularly about whether you still need treatment with BIJUVA

Do not take BIJUVA if you:

  • have any unusual vaginal bleeding. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause
  • currently have or have had certain cancers. Estrogens may increase the chances of getting certain types of cancers, including cancer of the breast or uterus. If you had cancer, talk with your healthcare provider about whether you should take BIJUVA
  • currently have or have had blood clots
  • had a stroke or heart attack
  • currently have or have had liver problems
  • have been diagnosed with a bleeding disorder
  • are allergic to BIJUVA or any of its ingredients
  • are pregnant, think you may be pregnant, or plan to become pregnant, or are breastfeeding.

WARNINGS

Tell your healthcare provider about all of the medicines you take and all of your medical conditions, including if you:

  • have high levels of fat in your blood (triglycerides)
  • have any unusual vaginal bleeding
  • have certain medical conditions that may become worse while you are taking BIJUVA such as: asthma (wheezing), epilepsy (seizures), diabetes, migraine, a genetic problem called porphyria, endometriosis, lupus, angioedema (swelling of the face or tongue), hypertension (high blood pressure), problems with your heart, liver, thyroid or kidneys, benign breast disease, have high calcium in your blood, are going to have surgery or will be on bed rest, are pregnant or think you may be pregnant, or are breastfeeding.

Call your healthcare provider right away if you get any of the following warning signs:

  • New breast lumps
  • Unusual vaginal bleeding
  • Changes in vision or speech
  • Sudden new severe headaches
  • Severe pains in your chest or legs with or without shortness of breath, weakness and fatigue
  • Vomiting.

The most common side effects of BIJUVA include:

  • Breast tenderness
  • Headache
  • Vaginal bleeding
  • Vaginal discharge
  • Pelvic pain.

USE

BIJUVA (estradiol and progesterone) capsules, 1mg/100mg, is used after menopause to reduce moderate to severe hot flashes in women with a uterus. BIJUVA is a prescription medicine that contains two hormones, estrogen and progesterone.



The risk information provided here is not complete. To learn more, review the BIJUVA Patient Information and talk about BIJUVA with your healthcare provider or pharmacist.

These are not all the possible side effects of BIJUVA. You may report side effects to the FDA at www.fda.gov/medwatch or by calling 1-800-FDA-1088. You may also report side effects to TherapeuticsMD at 1-888-228-0150.